spontaneous gene mutation
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Mutation — A permanent change, a structural alteration, in the DNA or RNA. In humans and many other organisms, mutations occur in DNA. However, in retroviruses like HIV, mutations occur in RNA which is the genetic material of retroviruses. In most cases,… … Medical dictionary
Gene — The basic biological unit of heredity. A segment of deoxyribonucleic acid (DNA) needed to contribute to a function. An official definition: According to the official Guidelines for Human Gene Nomenclature, a gene is defined as a DNA segment that… … Medical dictionary
Mutation — For other uses, see Mutation (disambiguation). Part of the Biology series on Evolution … Wikipedia
mutation — mutational, adj. mutationally, adv. /myooh tay sheuhn/, n. 1. Biol. a. a sudden departure from the parent type in one or more heritable characteristics, caused by a change in a gene or a chromosome. b. an individual, species, or the like,… … Universalium
Gene — For a non technical introduction to the topic, see Introduction to genetics. For other uses, see Gene (disambiguation). This stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The… … Wikipedia
Mutation rate — In genetics, the mutation rate is the chance of a mutation occurring in an organism or gene in each generation (or, in the case of multicellular organisms, cell division). The mutation frequency is the number of individuals in a population with a … Wikipedia
Point mutation — Illustration of three types of point mutations. A point mutation, or single base substitution, is a type of mutation that causes the replacement of a single base nucleotide with another nucleotide of the genetic material, DNA or RNA. Often the… … Wikipedia
One gene-one enzyme hypothesis — The one gene one enzyme hypothesis is the idea that genes act through the production of enzymes, with each gene responsible for producing a single enzyme that in turn affects a single step in a metabolic pathway. The concept was proposed by… … Wikipedia
Haemophilia — Classification and external resources Deficiency in coagulation factor VIII is the most common cause of haemophilia. ICD 10 D … Wikipedia
Haemophilia in European royalty — Haemophilia figured prominently in the history of European royalty in the 19th and 20th centuries. Queen Victoria, through two of her five daughters (Princess Alice of the United Kingdom and Princess Beatrice of the United Kingdom), passed the… … Wikipedia
evolution — evolutional, adj. evolutionally, adv. /ev euh looh sheuhn/ or, esp. Brit., /ee veuh /, n. 1. any process of formation or growth; development: the evolution of a language; the evolution of the airplane. 2. a product of such development; something… … Universalium
